ea0092ps3-29-03 | Treatment 2 | ETA2023
Piticchio Tommaso
, Belfiore Antonino
, Malandrino Pasqualino
, Trimboli Pierpaolo
, Gambero Federica
, Scuto Andrea
, Volpe Salvatore
, Di Benedetto Guenda
, Dario Tumino
, Le Moli Rosario
, Privitera Grete
, Pulvirenti Alfredo
, Frasca Francesco
Background: Tyrosine kinase inhibitors (TKIs) are modern antineoplastic molecules widely used in the medical treatment of many cancers including iodine refractory differentiated thyroid carcer (DTC) and advanced medullary thyroid cancer (MTC). In patients with thyroid gland, TKIs frequently cause a destructive and/or autoimmune thyroiditis with consequent hypothyroidism. However, authors have reported unexpected TSH increase or hypothyroidism even in patients with total thyroi...